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Notably, all these studies are preclinical and involve experimental animal models, encompassing diverse pathways and targets

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Thus, poorer dynamics of phylloquinone and MK4 in the lipid bilayer owing to the lengthy side chains may give rise to their localization within the lipid membrane, suppressing their autoxidation and the consumption of reducing equivalents from NADH or NADPH (Extended Data Fig

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[Google Scholar] 133.Valiante V, Baldin C, Hortschansky P, Jain R, Thywien A, Straburger M, et al