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HBV vaccination guidelines for infants recommend the following first dose as soon as possible following birth, ideally within the first 24 hours and within the first 12 hours if the person giving birth is HBV-positive second dose at 1 to 2 months old third dose at 6 months old After completing the three doses, infants will need to see a doctor at 9 to 12 months old to check whether the vaccine has been effective and there is no HBV infection present