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Rather than delivering glutathione directly, it supplies cysteine, the amino acid that the body is most commonly short of when glutathione production falls behind demand

300 Natural compounds such as curcumin also induce autophagy in gastric cancer cells, marked by increased Beclin-1, Atg3, Atg5, and LC3-II expression

Quercetin and other flavonoids are known to behave as mild prooxidants resulting in the upregulation of protective genes, such antioxidant enzymes, glutathione, and cytoprotective enzyme Heme Oxygenase HO-1 mediated by activation of the Nuclear factor erythroid 2-related factor 2 (NRF2), a transcription factor upregulating antioxidant response, expression of antioxidant enzymes, and cytoprotective proteins (Ma and He 2012)

269 , C75056, (1995)

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