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Glutathione peroxidase (GPx)-deficient mice spontaneously develop colitis 4

since in this species, there is evidence that different infectious, parasitic, metabolic diseases and other conditions such as stress and ageing are associated with oxidative stress [56,57,58,59,60,61,62]

More interestingly, several studies support that ferroptosis and necroptosis are alternative pathways, such that resistance to one pathway sensitizes cells to death via the other pathway

The Ras protein is an upstream protein in the MAPK pathway that controls subsequent cascade reactions

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