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The free-energy landscape built with the first two eigenvectors of the PCA analysis showed a less rugged surface and a smaller number of energy minima in the holo-form, in contrast with the behavior of the apo-form (Fig 2)

Sulfhydryl groups can undergo post-translational modifications, such as S-nitrosylation and S-glutathionylation, which modulate protein activity and signaling cascades

however, it has certain limitations in terms of side effects and a limited therapeutic window ( As a continuation to researches concerned with natural compounds, phytic acid (PA) was evaluated in this study in APAP induced hepatoxicity based on its antioxidant properties and its ability to modulate iron metabolism

GHK-Cu: GHK-Cu focuses on copper-dependent enzymatic activity and is primarily studied for skin/tissue remodeling

Use of leukemic dendritic cells for the generation of antileukemic cellular cytotoxicity against Philadelphia chromosome-positive chronic myelogenous leukemia