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N-acetylcysteine N-acetylcysteine (NAC) replenishes glutathione by acting as a donor of cysteine, which helps maintain redox balance in cells, detoxify reactive oxygen species (ROS) produced by the culprit drug, and reduce specific T cell stimulation, and is effective only when given early

This amorphous state can significantly enhance the dissolution rate and saturation solubility, leading to improved absorption (150)

Fe 2 + /3 + -A complexes produce ROS, confirmed in vitro (Kim and Lee, 2021)

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Without glutathione, the brain cannot handle free radicals as well, and more damage occurs