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L'utilisation de la version buvable ou par voie injectable est cependant rserve au traitement des carences lies une malabsorption digestive de la vitamine B12, ou pour le traitement de la carence lie un apport alimentaire insuffisant lorsque le recours la voie orale n'est pas envisageable

However, bacterial and insect contamination in food stuffs protects them to some extant against deficiency

Those facts were confirmed in animal models of IGF-I deficiency as they often exhibit increased ROS production and decreased NO bioavailability, mimicking the vascular aging phenotype[294]

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