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However, complete inactivation of monophenolase activity in jr PPO1-wt was achieved only when both activity controller residues were mutated (Asn240Lys/Leu244Arg and Asn240Thr/Leu244Arg)

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doi: 10.3389/fimmu.2024.1365554 107 WeissG.RasmussenS.Nielsen FinkL.JarmerH.Nhr NielsenB.FrkiaerH

Next, we examined the redox status of oocytes to assess mitochondrial function and developmental potential

In the bloodstream's neutral pH environment (~ 7.4), the engineered NDDSs carry a net negative charge

They found that OCCC cells were more resistant to carboplatin than OSC cells, and that the inhibition of GSH production by BSO sensitized these cells to carboplatin, both in vitro and in vivo [57]