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It is a rare skin disorder that causes velvety, dark brown-blackish patches that look like dirt spots

Intriguingly, in the CoPP:GSH/ADPVO-bound dataset, only a small subset of particles (8.9%) adopted the expected occluded conformation with a closed NBD dimer (Supplementary Fig 9)

27 , 17261741.e1725 (2019)

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