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These effects are particularly evident in patients with obstructive sleep apnea (OSA), where chronic intermittent hypoxia leads to sustained activation of the HIF-1/NF-B axis, promoting inflammation, increased sympathetic activity, and systemic hypertension [55,56]

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In our study, findings demonstrated that interventions involving CO, GSH, and their combined regimen both in traditional and NP formulations resulted in significant reductions in NGAL and KIM-1 concentrations in the gentamicin-induced AKI model

Among other things, vitamin B12 is also required for the creation of red blood cells and DNA

Bertheloot D, Latz E, Franklin BS (2021) Necroptosis, pyroptosis and apoptosis: an intricate game of cell death