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It encompasses a variety of conditions that impair the heart and blood vessels, such as atherosclerosis (AS), myocardial infarction (MI), hypertension (HTN), and heart failure (HF) [41], resulting in a huge social and economic burden

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Hyaluronic acid binds to CD44 within a shallow groove located between the hook region and the 56 loop (Fig

As illustrated in Figure 3, RF achieved one of the highest and most stable cross-validated AUC values across all five folds (Figure 3A), and exhibited favorable discriminative ability in ROC curve analysis on the test set (Figure 3B)