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As a result of strong membrane lipid peroxidation and oxidative stress, mitochondrial cristae are reduced or absent, the outer mitochondrial membrane is ruptured, and the mitochondrial membranes are condensed, resulting in weaker plasma membrane selective permeability and increased oxidative stress

doi:10.1016/s2468-1253(16)30003-6 64Van Assche G, Dhaens G, Noman M, et al

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doi: 10.1089/jpm.2020.0218.Epub 2020 Sep 23 Weisz RD, Fokin AA, Lerner V, Flynt A, Macias-Perez I, Pavliv L, Crawford M, Puente I