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Participants either followed an exclusion diet, defined as gluten and casein free regimen adopted independently by families before enrolment, or an unrestricted die, an important source of baseline heterogeneity, as dietary patterns were not experimentally assigned

Lan H, Yang N, Nikolic-Paterson D, Yu X, Mu W, Isbel N, Metz C, Bucala R , Atkins R

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(2021) demonstrated that exposure to simulated microgravity for a duration of 3 weeks resulted in impairment of the intestinal mucosal barrier, characterized by reduced goblet cell count, enlarged intercellular space, downregulated adhesion molecules, and increased intestinal permeability in rats