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If you suspect you've experienced a side effect from a vitamin B12 supplement, you can report it through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)

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This is because vitamin B12 acts as a cofactor for neurotransmitters like serotonin and dopamine, both of which are key regulators of mood and emotion

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DAMPs serve as alarm signals within the innate immune system, alerting cells to any damage or to the presence of non-native microbes, which in turn activates host immune responses 68