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In addition to miRNAs, the protein cargo of EVs also plays a significant role in the pathogenesis of CF lung disease

Weinberg-Shukron A, Rachmiel M, Renbaum P, Gulsuner S, Walsh T, Lobel O, et al

LZ: Methodology, Writing review & editing

Ferlay J, Bray F, Pisani P, et al

For instance, poor metabolizers are more likely than other individuals to experience drug toxicity, and less likely to gain benefit from the analgesic codeine, a prodrug which is metabolized by CYP2D6 to morphine, the active drug