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Gene expression profiling in response to Se treatment in the Se hyperaccumulator Astragalus chrysochlorus revealed that DNA (cytosine-5)-methyltransferase CMT3-like was upregulated, indicating a potential involvement for Se, as aqueous sodium selenate, in the regulation of epigenetic processes [112]

More rigorous clinical studies and higher-quality evidence are needed to establish the strength and cause-and-effect relationship of this correlation

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