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Biochem J 429(1):4351

Diabetic rats and high fat diet (HFD)-fed mice subjected to 4 weeks of treatment with myriocin, an SPT inhibitor, had lower body weight, fasting blood glucose, plasma insulin, and circulating free fatty acid levels compared to diabetic and obese controls (40)

doi: 10.1021/jf035241f

The activity of GPX4 is regulated by multiple layers, such as epigenetic regulation, transcription regulation and post-translational regulation, among which these regulatory processes involve phosphorylation, ubiquitination, succination and glycosylation (Cui et al., 2022)

Baskol G, Demir H, Baskol M, Kilic E, Ates F, Karakukcu C, Ustdal M (2006) Investigation of protein oxidation and lipid peroxidation in patients with rheumatoid arthritis