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A componenttarget network was constructed and visualized using Cytoscape software, consisting of 238 nodes (11 compounds and 30 genes) and 237 interaction edges (Fig

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From this perspective, it is interesting to note that we recently reported that transferrin plays an important role in both high dietary iron-induced liver fibrosis and carbon tetrachloride (CCl 4 )-induced liver fibrosis in mice, and inhibiting ferroptosis potently prevented these effects