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In addition, the increased production of pro-inflammatory cytokines induced by gut dysbiosis, potentially compromises the BBB integrity [19], leading to the entry of toxins, peripheral inflammatory compounds, and T cells into the brain

Graves et al., 2015)

In these studies, the most commonly used antioxidants were Vitamin E, Vitamin C , carnitines, N-acetyl cysteine, co-enzyme Q10, zinc , selenium, folic acid, and lycopene

[DOI] [PMC free article] [PubMed] [Google Scholar] Zaplatic, E

In all cases treatment with pyridoxine or PLP itself alleviates the seizure tendency ( It has been hypothesized that a deficiency of PLP may cause seizures through suboptimal inhibitory GABAergic neurotransmission