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Herein, using in vitro TNBC models including cell lines with GPX4 or PC suppressed, together with murine models of obesity and TNBC growth and metastasis, we aimed to characterize (i) interactions between GPX4, PC, and lipid oxidative stress in TNBC cells, and (ii) the effect of GPX4 suppression, alone or in combination with chemotherapy or immunotherapy, on TNBC progression

J Soc Integr Oncol 6:122 Naylor GM, Gotoda T, Dixon M, Shimoda T, Gatta L, Owen R, Tompkins D, Axon A (2006) Why does Japan have a high incidence of gastric cancer

L.G.Z., T.P.M., and the Childrens Research Institute Metabolomics facility are supported by CPRIT grant RP240494

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Methylation occurs not only in specific regions of the X chromosome, such as retrotransposon elements and centromere regions, and the result of methylation in these regions usually leads to genes inactivation (13)