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Description

10.3390/ijms24032703 Int

3 FAHF-2, B-FAHF-2, and EBF-2 for IgE-mediated allergic diseases FAHF-1 is a traditional Chinese formula composed of eleven herbs including ling zhi ( Ganoderma ), fu zi ( Aconiti lateralis radix praeparata ), wu mei ( Mume fructus ), chuan jiao ( Zanthoxylum pericaprium ) , xi xin ( Asari radix et rhizoma ), huang lian ( Coptis rhizoma ), huang bai ( Phellodendri cortex ), gan jiang ( Zingiberis rhizoma ), gui zhi ( Cinnamomum ramulus ), ren shen ( Panax ginseng ) and dang gui ( Angelica sinesis radix )

It has a greater potency toward FXR than OCA (EC 50 = 0.03 M vs EC 50 = 0.09 M for OCA)

Possible solution: Rigorously pre-clear lysate with GSH beads

Standard research washout protocols recommend 6090 days before conception, extrapolated from tissue retention models and the absence of pregnancy-specific pharmacokinetics