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Safety and side effects: A meta-analysis of multiple studies in COPD patients showed no significant adverse effects at doses ranging from 600 mg to 3g/day.[ref] Studies in healthy adult athletes go up to 20g/day (not recommending this, just including it for safety).[ref] Conversely, in Parkinsons patients, there was a high number of adverse events at 6g/day of NAC

In animals, proper functioning of the IGF signaling pathway is essential for normal growth, and any disruption caused by zinc-related factors can have significant consequences for growth and development [131, 132]

Kubo, H., et al

Mechanisms of daratumumab resistance However, after several months of treatment with daratumumab, patients face a progression of their disease because of acquired resistance [78]

These outcomes reflect observed biomarker and pathway changes under controlled conditions and are not established therapeutic claims