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Furthermore, AI-driven drug repositioning based on pathway profiling revealed that Tanshinone IIA inhibits oxidative stress-induced hepatic fibrosis by stabilizing the "closed" conformation of Keap1 and enhancing its ubiquitinated degradation of Nrf2, a prediction validated by HDX-MS

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The algal material collection was conducted in accordance with the local and national regulations

10.1007/s13197-019-04065-1 184 SongS.DangM.KumarM