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The epithelial tight junction proteins, the most apical component of epithelial intracellular junctions, equip IECs with this function, which seals the paracellular space between the cells and tightly restricts the transport of hydrophilic molecules 22,23,24

Subcutaneous injection may produce localized redness, minor swelling, or bruising at the injection site, which resolves within 24 to 48 hours