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In another hand, while most reports appear to implicate IGF-I as a potential mediator of pathological changes in the diabetic kidney[364, 365], IGF-I is also protective against oxidative stress and apoptosis induced by high levels of glucose in cultured mesangial cells

When the molar ratio of the coordinating functional groups remains constant, the absorbance observed at 584 nm for the dimer was larger than that of the monomer peptide, indicating that D-P possesses better coordination efficacy and greater stability than M-P (Fig

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Immunofluorescence The 6.5 10 4 hDP cells were transferred into a 35-mm confocal dishes (SPL life sciences, Korea) and then exposed to NTAPP 24 h after seeding