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doi: 10.1038/s41580-024-00703-5 52 WenPSunZGouFWangJFanQZhaoDet al

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"One common ingredient used is antioxidants (such as vitamins C and E) which can lower oxidative stress on the follicle that can be involved in the aging, and thus graying, process." Additionally, the accumulation of hydrogen peroxide in the hair shaft during aging is also thought to lead to hair shaft bleaching, she adds

Immunohistochemistry of brain tissues from mice treated with GHK showed evidence of decreased inflammation and increased labeling of histone deacetylase 2, suggesting that in addition to an anti-inflammatory effect, GHK may be triggering an epigenetic pathway in the amelioration of cognitive impairment in aging mice

& Gumbiner, B