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However, when it is disturbed, neurodegeneration can result (Parakh et al., 2013

Because supplementation with iron can have unwanted side effects in those with preexisting infections, especially malaria, routine iron supplementation should be accompanied by malaria detection and treatment strategies

doi: 10.3389/fphar.2026.1755175 Received 26 November 2025 Revised 21 January 2026 Accepted 20 February 2026 Published 09 March 2026 Volume 17 - 2026 Edited by Roland Bcker, Charit University Medicine Berlin, Germany Reviewed by Mark Lloyd Dapar, Central Mindanao University, Philippines Kishor Jain, Sinhgad Institutes, India Updates Copyright 2026 Kayesh, Kohara and Tsukiyama-Kohara