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J.PetrieJ

Additionally, as CBD has not affected neither transcription nor expression of skin moisturizing factor-related genes, the observed results were due to AQP3 modulation, probably by activation of PPAR-

On the contrary, in the colon, DCA and taurocholic acid could activate TGR5 on ECs and enteric neurons to stimulate the release of TPH1 and 5-HT, thus enhancing colonic motility (Zheng et al., 2022)