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(PubMed) Johnston CS, Kolb WP, Haskell BE

The truncated peptide consisting of the amino acids 1320, WVELHFSN led to the strongest signal with a 14-fold signal increase compared to the non-truncated peptide 120 (Fig

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In summary, elevated levels of inflammatory factors partly initiated by microglia and other recruited immune cells causes a phenotypic switch in astrocytes that contributes to functionally perpetuating inflammation via the release of pro-inflammatory cytokines and recruitment of peripheral immune cells