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Therefore, HGF creates a microenvironment through interaction between cancerous cells and adjacent stroma, increasing the further development and invasiveness of cancer [19]

Estrella JS, Hofstetter WL, Correa AM, Swisher SG , Ajani JA, Lee JH, Bhutani MS, Abraham SC, Rashid A, Maru DM

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Investigations using CF cell lines reveal intrinsic SOD alterations linked to CFTR dysfunction

The loss of SOD activity reflects increased oxidative and nitrative stress in asthmatic patients, suggesting that SOD serves as a surrogate marker of oxidative stress and asthma severity 45