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Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling

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This result suggests that some ischemia-associated metabolite changes in pericardial fluid may be reflected in circulating metabolite profile, which therefore represents a potential and more easily accessible perioperative tool for detecting the metabolic status of the myocardium

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The GSTM1 gene is responsible for the removal of xenobiotics, carcinogens and products of oxidative stress (Traka et al ., 2008)