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The findings indicated that AST/Bex treatment restrained transcription and activity of the amyloidogenic enzyme BACE1, consequently decreasing A oligomers as well as 80-kDa intracellular APP/A species

This demographic focus is crucial for understanding the potential variable efficacy of GLP1-agonist treatments due to genetic diversity

Oxidative stress is observed when there is an imbalance between the ROS generation and elimination, due to the impaired antioxidant defence system and/or the exacerbated activity of pro-oxidant enzymes [37]

Sections (50 m thick) were cut using a cryostat and individually collected in 96-well culture plates filled with 0.1 M phosphate buffer (PB)

10.1007/s12264-015-1555-3 119 LiddelowS