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Several biomarkers, such as GPX4 and p53, have been identified for their regulatory effect on ferroptosis, and some compounds targeting these molecules to induce ferroptosis have already been found [9, 10]

Vitamin D3: Vitamin D3 plays an enormous role in the development and function of the brain

Inhibition of MCAD in GBM cells (either genetically or pharmacologically) leads to the accumulation of medium-chain FAs, lipid peroxidation, and mitochondrial damage, resulting in apoptosis [124].An interesting use of FAO by glioma cells is to evade anti-tumor responses induced by radiotherapy

The transfected NUGC-4, MKN-45 and NUGC-3 cell lines were seeded into 96-well culture plates and incubated with CCK-8 reagent for 3 h

D., & Cavanaugh, J