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For chemicals that accumulate to a significant extent via diet, bioaccumulation can be estimated from the bioaccumulation factor (BAF) using food chain multipliers (FCM), which for substances with Log K OW between 6.0 and 7.5 are 13 and 2324 for trophic level 3 (planktivorous) and level 4 (piscivorous fish), respectively (USEPA, 2000): The ratio between the estimated bioaccumulation factor and the partition constant K PE ,is a theoretical estimate of R s,o,m,lipid at chemical equilibrium, therefore RR

FASEB j 9(12):11731182 Kyselova Z (2010) Different experimental approaches in modelling cataractogenesis: an overview of selenite-induced nuclear cataract in rats

doi:10.1016/s2666-7568(24)00094-1 3

actinomycetemcomitans , changes in the intestinal microbiota, and glucose metabolism [155]