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Similarly, mice with genetic TLR4 or TLR3 knockout do not develop hyperalgesia after treatment with cisplatin [17, 110]

[76] Defective DNA repair has been linked to neurodegenerative disorders such as Alzheimer's disease, amyotrophic lateral sclerosis, ataxia telangiectasia, Cockayne syndrome, Parkinson's disease and xeroderma pigmentosum

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