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Key proteins such as P62 and Beclin-1 regulate autophagy and have emerged as important markers for disease progression, with P62 involved in both autophagy and inflammasome modulation 9

Moreover, oxidized HDL loses anti-inflammatory and antioxidant functions, hence, it is unable to remove oxidized LDL and oxidized products existing in cells (101,102)

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Biochemistry 38(42):1378713794 Dekker LV, Parker PJ (1997) Regulated binding of the protein kinase C substrate GAP-43 to the V0/C2 region of protein kinase C-delta

+ - Current animal studies suggest BPC-157 is protective for kidneys, showing it can improve function and mitigate damage from injuries like ischemia-reperfusion, but human data is limited, so caution is advised, especially for those with pre-existing kidney issues, and professional medical advice is essential before use