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The theoretical basis for synergy involves the concept of recovery periodization. Just as athletes periodize training loads to optimize adaptation, strategic timing of recovery modalities may enhance overall outcomes

Some people report improvement within days for acute injuries, while chronic conditions may take weeks

As mentioned, this unusual combining effect in hemostasis was recently evidenced with bleeding/thrombocytopenia after amputation, with or without anticoagulant and aspirin administration, abdominal aorta anastomotic site-thrombosis, both being counteracted [1,2]