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Every IV is started and monitored by a licensed medical professional

White et al, 2016)

That decline correlates with reduced skin elasticity, slower wound healing, and thinning hair density

Thus, folate builds up in the form of 5mTHF (the "methyl trap") and there is less folate in the forms CH 2 -THF and 10f-THF that are the substrates for thymidylate and purine synthesis, respectively