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The RAI therapy, while effective, often causes hypothyroidism, and this requires lifelong replacement with thyroid hormones

7nAChRs are involved in immunity, inflammation, and neuroprotection in non-neuronal cells such as astrocytes, microglia, dendritic cells, lymphocytes, macrophages, and endothelial cells (Table

For instance, senescent hepatocytes located in the peritumoral region suppressed the immune response, thereby promoting the development of hepatocellular carcinoma (HCC) [41]

doi: 10.1016/j.canlet.2010.07.014 106 Della BellaCSoluriMFPuccioSBenagianoMGrassiABitettiJet al