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Patients with conditions such as obesity, diabetes, and lipodystrophy often have low levels of serum IGF-1

& Ros, J

Regulates actin polymerization, promotes angiogenesis, reduces inflammation at the injury site

& Xu, W

On the other hand, the adverse events of GLP-1 drugs have been extensively characterized from large randomized trials with placebo controls and, in the United States, from reports derived from 12% of Americans who are currently taking these drugs