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Certain cancers, especially those of the stomach, pancreas, or blood (such as leukemia or lymphoma), can impact available Vitamin B12 by either blocking or disrupting the bodys absorption and/or increasing the physiological need for Vitamin B12

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Danila DC, Haidar JNS, Zhang X, Katznelson L, Culler MD, Klibanski A

RNA Extraction and Quantitative Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) Total RNA was extracted from cellular and cerebral samples using TRIzol reagent (Invitrogen, Carlsbad, CA, United States)