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Residues in this region are conserved in both human and Plasmodium Trx-2 (highlighted by red colored box in Fig

et al (2014) J Biol Chem

Metallothionein-1G (MT1G) have a high content of cysteine residues that bind various heavy metals, these proteins are transcriptionally regulated by both heavy metals and glucocorticoids, such as iron, zinc and copper 8