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10.1007/s00508-020-01758-y 139 PellegriniM.SenniC.BernabeiF.CiceroA

We further revealed that the protective effect of NE and DA against glutamate-induced oxidative cytotoxicity was mediated through inhibition of PDI-catalyzed dimerization of the neuronal nitric oxide synthase

The Journal of Alzheimer's Disease published a dose-response study showing peak spatial learning enhancement at 1mg/kg administered subcutaneously three times weekly over four weeks, while doses above 3mg/kg showed no additional benefit and increased off-target receptor binding

It was first formally described in the scientific literature in 1993 by a team of researchers led by Sikiric and colleagues

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