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Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients

[amp]]Gamma;-mangosteen, an autophagy enhancer, prevents skin-aging via activating keap1/nrf2 signaling and downregulating mapks/ap-1/nf-Kb-mediated mmps

Liao X, Zhan Y, Yang Y, Luo Y, Hu SH

Abbreviations ANOVA: Analysis of variance AQP-3: Aquaporin-3 CAT: Catalase CVOs: Circumventricular organs DW: Distilled water ELISA: Enzyme linked immunosorbent assay GH: Growth hormone GPx: Glutathione peroxidase IBM: International business machines MDA: Malondialdehyde MSG: Monosodium glutamate NC: Normal control OS: Oxidative stress OXT: Oxytocin OXTR: Oxytocin receptor PBS: Phosphate buffer solution PCR: Polymerase chain reaction PRL: Prolactin PRLR: Prolactin receptor ROS: Reactive oxygen species SOD: Superoxide dismutase SPSS: Statistical package for social sciences References Abdulghani, M

It is theorized that the increased level of ROS is the primary reason for mitochondrial susceptibility to mutations