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MAO-A is primarily responsible for the breakdown of 5-HT and NE and plays an important role in psychiatric conditions such as depression associated with PD

Follow-up cadence built into the program A typical Epithalon cycle includes a 10-day loading phase followed by a structured observation window

However, significant heterogeneity in study design, measures of inflammatory biomarkers and analysis techniques 193 , makes evaluation of inflammatory markers compared to other markers of progression in PD difficult, and their clinical usefulness remains uncertain

doi: 10.1038/s41564-024-01907-3 443 WangY.WangK.Masso-SilvaJ