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All FDA-approved AMPs were discovered in Gram-positive soil bacteria, and 98% of known AMPs also come from natural sources (skin secretions of frogs and toxins from different species)

qPCR analysis was performed to measure the mRNA level of c-Fos ( g ), c-Jun ( h ) and Smurf1 ( i ) in indicated cells (n = 4 technical repeats from one of three independent experiments)