These microbial shifts are accompanied by altered purine metabolism in the substantia nigra, linking gut modulation to neuroprotection
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European journal of nutrition , 54 (2), 251-263
Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations 2-OGC: 2-oxoglutarate AD: Alzheimers disease DIC: Dicarboxylate DISC: Death-inducing signaling complex ER: Endoplasmic reticulum GCL: Glutamate-cysteine ligase GGT: -glutamyl transferase GR: Glutathione reductase Grx: Glutaredoxin GS: GSH synthetase GSH: Glutathione GSH: Reduced glutathione GSSG: Oxidized glutathione GSTs: Glutathione S-transferases H 2 O 2 : Hydrogen peroxide HCC: Hepatocellular carcinoma HCV: Hepatitis C virus HO : Hydroxyl radical mGSH: Mitochondrial GSH MIM: Mitochondrial inner membrane MIS: Mitochondrial intermembrane space MOM: Mitochondrial outer membrane NAPQI: N-acetyl-p-quinoneimine NMDA: N-methyl-D-aspartate O 2 : Superoxide anion radical PD: Parkinsons disease RNS: Reactive nitrogen species ROS: Reactive oxygen species SAM: S-adenosyl-l-methionine Trxs: Thioredoxins References Anasagasti MJ, Martin JJ, Mendoza L, Obrador E, Estrela JM, McCuskey RS, Vidal-Vanaclocha F (1998) Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature
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