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We developed an assay to inform the design and characterization of future KRAS inhibitors using the Y137W mutation, which was selected based on the location of a naturally-occurring Trp in some RAS family members

Defects in the gene, most notably the C677T gene polymorphism, may result in low 5-MTHF levels, resulting in hypohomocysteinemia.5 The effects of having hypohomocysteinemia are mainly due to the prolonged depletion of cysteine

Molecular mechanisms and in vitro antioxidant effects of lactobacillus plantarum MA2