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Chronic impairment of mitochondrial bioenergetics and -oxidation promotes experimental AKI-to-CKD transition induced by folic acid

Porphyria is a group of inherited disorders caused by an abnormality in one of the steps your body uses to make heme

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For example, tetrahydrobiopterin (BH4) deficiency causes a reduction of activity in the BH4-dependent phenylalanine hydroxylase reaction and results in a form of phenylketonuria (PKU)