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Atovaquone, a repurposed antimalarial drug, acts as a selective OXPHOS inhibitor by targeting the CoQ10-dependent mitochondrial complex III, causing electron leakage, ROS production, and cell death, as observed in Fhit-deficient lung cancer cell lines

Al Jasem Y, Khan M, Taha A, Thiemann T

In the cellular context, these aberrant interactions can disrupt physiological processes by sequestering various proteins essential for normal cellular functions, resulting in diffused aggregates that may act as molecular triggers for LB nucleation

Most patients need many drip treatments per week for a duration of six to eight weeks due to the type of their skin and the outcome they want

E.Stenkiewicz-WiteskaJ.De MaeyerR